This event will discuss the path forward for the Partnership in Action, following the successful inception of the Global Pilot Programme on Science, Technology, and Innovation (STI) for the SDGs roadmaps. The Partnership in Action is conceived as a multi-stakeholder, informal technical group to support the STI Roadmap work in the context of the Technology Facilitation Mechanism. Its aim is to create the political momentum, drive practical solutions, and mobilize public and multi-stakeholder engagement. The demand to further promote the deployment of STI for SDGs roadmaps was triggered by the need to accelerate efforts to close the digital divide and support the digital inclusion of disadvantaged groups especially following the COVID-19 pandemic. The Partnership in Action will serve as a platform to strengthen the development and implementation of STI for SDGs roadmaps, through the Global Pilot Programme first launched in July 2019. Roadmaps are currently being developed in six pilot countries (Ethiopia, Ghana, India, Kenya, Serbia, and Ukraine). The event is aligned with this year’s theme of the High-Level Political Forum on sustainable development (HLPF) and builds on the outcome of the STI Forum 2021. This event is built on the work of the UN Inter-Agency Task Team sub-working group on STI for SDGs Roadmaps co-led by UN-DESA, the World Bank, UNESCO, EC/JRC, and UNCTAD. This event is supported by Ghana and is co-organized with Japan, UN-DESA, EC/JRC, UNECA, UNESCO.