The political declaration adopted by the UN General Assembly when marking the 75th anniversary of the United Nations reflects world leaders' understanding of the critical moment we are facing in UN history. It states “Our world is not yet the world our founders envisaged 75 years ago. It is plagued by growing inequality, poverty, hunger, armed conflicts, terrorism, insecurity, climate change, and pandemics. People in different corners of the world are forced to make dangerous journeys in search of refuge and safety. The least developed countries are falling behind, and we still have not achieved complete decolonization. All this calls for greater action, not less.” The Declaration also underlines the value of multilateralism, which could be seen as the primary required tool to face the current world interconnected challenges. According to world leaders, the only way to confront current threats and succeed is addressing them “through reinvigorated multilateralism.” A question arises. What does “reinvigorated multilateralism” mean? What should a strong multilateralism look like? In which ways the reinforced multilateralism will support those that the actual order is still leaving behind? We need to answer those questions as a first step towards the committed reinvigorated multilateralism building. The Declaration on the Commemoration of the Seventy-Fifth Anniversary of the United Nations provides impetus for rethinking multilateralism. The Secretary-General appealed to Build Back Better, and the call made by Member States to ignite a Decade of Action and Delivery pointed in the same direction. And the 2030 Agenda still provides the political guidance we need to create a strengthened multilateralism. Furthermore, the 2021 High-level political forum bird’s eye view of the world situation regarding SDGs and the impact of the global pandemic need to be part of this ecosystem of reframing a new narrative. Twelve critical themes were highlighted by Member States as part of their common Declaration: leave no one behind; protect our planet; promote peace and prevent conflicts; abide by international law and ensure justice; place women and girls at the center; build trust; improve digital cooperation; upgrade the United Nations; ensure sustainable financing; boost partnerships; listen to and work with youth; and improve preparedness for future challenges and crises. Each issue in the list is directly linked to Sustainable Development. Almost all of them are part of the SDGs. That means that a reinvigorated multilateralism should be the expression of the sustainable development commitment in world governance, particularly the commitments in the 2030 Agenda and the SDGs. The HLPF mandate of providing policy guidance in the path towards Sustainable Development achievement made necessary to discuss this issue in its works framework.